The name bubonic plague is specific for this form of the disease, which enters through the skin, and travels through the lymphatic system . The Black Death was an outbreak of disease that killed millions of people across Europe and Asia. Around 50 million people were killed by the bubonic plague, and was at its worst between 1347 and 1351. The San Francisco plague of 1900–1904 was an epidemic of bubonic plague centered on San Francisco 's Chinatown. Bubonic plague (part of First plague pandemic) Unknown Plague of Sheroe: 627–628 … 000596.

Bubonic plague is the best-known form of the disease plague, which is caused by the bacterium Yersinia pestis. It was the first plague epidemic in the continental United States. The disease may have started in Asia. The epidemic was recognized by medical authorities in March 1900, but its existence was denied for more than two years by California's Governor Henry Gage. Most people think that the disease was the bubonic plague.